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While effective for regulating periods and reducing androgen-related symptoms, contraceptives do not address the underlying metabolic dysfunction and are not suitable for women trying to conceive

Patients with type 2 diabetes who have established diabetic retinopathy at treatment initiation face the highest risk, particularly when experiencing rapid A1c reductions within the first 16 weeks of therapy

Lowest entry tier and a strong fit for needle-free starters

In other words, while recognising obesity as a chronic disease might reduce weight stigma, using pharmacological approaches alone for obesity management could shift the emphasis away from an overhaul of the current obesogenic food environment that encourages overconsumption

Elevations were uncommon (1% of participants) and generally resolved without intervention

Researchers continue exploring patch technology, but developing a reliable formulation requires years of clinical validation