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While preclinical studies, primarily in animal models 17,18 , suggest a potential beneficial effect of GLP-1 RAs on mood and behavior, the clinical evidence in humans remains unclear 19,20

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The Food and Drug Administration regulates most foods and dietary supplements under a postmarket framework, meaning theres no review of product claims before theyre available to consumers

Since none of the GLP-1RA are approved in pregnancy, a cohort study approved the potency of liraglutide, in early pregnancy, despite its adverse outcomes such as preterm birth, preeclampsia and gestational diabetes mellitus (GDM) (90)