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The most common are nausea, fatigue, constipation, and reduced appetite (which is the medication working but can occasionally be too pronounced and require a dose adjustment)

The challenge facing this strategy is that monotherapies often have varying pharmacokinetics and pharmacodynamics including half-life [69], meaning that the balance of target-receptor agonism may vary over time when using two different agents with varying profiles

For drinks, cold brew with no sweetener or a plain iced Americano are the cleanest choices