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The purpose of this review is to summarise the physiological effects as well as the therapeutic implications of the gut hormones glucagon-like peptide-1 (GLP-1), oxyntomodulin, peptide YY (PYY), and glucose-dependent insulinotropic peptide (GIP) in the treatment of obesity and type 2 diabetes

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Experimental research therefore uses GLP-RTas a model compound for studying incretin-mediated endocrine signaling and how multiple hormonal inputs interact within metabolic regulatory systems [3][5]

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