glp-1 substance abuse Anti-Obesity Rx and Alcohol and Use Disorders IUPHAR review – Glucagon-like peptide-1

Originally designed to manage type 2 diabetes (T2D), these drugs have rapidly expanded their therapeutic reach, offering significant benefits for obesity, cardiovascular disease, and beyond

It is primarily known for its role in maintaining glucose balance in the body

It covers every dose from the starting 0.25mg (5 units) all the way to 2.5mg (50 units)

GLP-1 RAs are effective and safe treatments for controlling blood sugar levels and reducing body weight, and evidence from large clinical trials also suggests that GLP-1 RAs may be renoprotective

Find answers to common questions about our medication subscriptions and medical review process.

Indeed, an important issue for the potential cognitive and mental health effects of GLP-1RAs, which our analysis cannot fully address, is whether these medications provide symptomatic relief only via their well-established cardiometabolic benefits, or by directly targeting physiopathological mechanisms behind cognitive and mental symptoms