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The synergistic effect of poor dietary quality and lack of exercise creates a fertile ground for the development and progression of metabolic disorders

[DOI] [PubMed] [Google Scholar] 38.Schirra J., Nicolaus M., Roggel R., Katschinski M., Storr M., Woerle H.J., Gke B

Quick Answer: Weight gain on tirzepatide can occur due to fluid retention, metabolic adaptation, inadequate dosing, medication interactions, lifestyle factors, or underlying medical conditions that counteract the medication's appetite-suppressing effects

doi: 10.3389/fnut.2026.1809416 Received 11 February 2026 Revised 24 April 2026 Accepted 11 May 2026 Published 02 June 2026 Volume 13 - 2026 Edited by Ivana arac, University of Belgrade, Serbia Reviewed by Dbora Luana Ribeiro Pessoa, Federal University of Maranho, Brazil Jiaqi Liu, University of Texas Health Science Center at Houston, United States Updates Copyright 2026 Song, Fang, Li, Fu, He, Gao, Tian and Gao

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Focus on complex carbohydrates like whole grains, fruits, and vegetables