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In the RCT (exenatide), patients on acetazolamide were excluded to better isolate the effect of exenatide during the 12-week trial period [14, 35]

On top of this, oral formulations do not require specific conditions of sterility and other precautions against possible particle contamination, which may also have cost implications

GLP-1RAs treatment significantly decreased the LFC measured using MRI (weight mean difference [WMD] = 3.01%
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Over that same period, economy-wide consumer prices rose only a small fraction as much
