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Control of satiety also occurs when GLP-1R + neurons in the nucleus tractus solitarius of the hindbrain are stimulated, and this occurs independently of aversion caused by activation of GLP-1R + neurons in the area postrema [36]

The pill is generally slightly less effective than injections

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They help define the magnitude of GcgR agonism that can be tolerated in the context of GLP-1R agonism, as well as the degree of additional efficacy that it might yet be possible to achieve

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