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Diabetes leads to a significantly accelerated incidence of various related macrovascular complications, including peripheral vascular disease and cardiovascular disease (the most common cause of mortality in diabetes), as well as microvascular complications such as kidney disease and retinopathy
The approval of semaglutide for chronic weight management has fundamentally changed obesity medicine, and semaglutide training for physicians has become an urgent clinical priority

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Off-label usage of GLP-1 weight loss drugs stacked with steroids for quick fat loss with minimal muscle wastage is a serious health concern

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