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Some people taking tirzepatide report increased sensitivity to cold temperatures

You chose the drug over discipline

And eventually, it may be evidence payers, clinicians, employers, and patients all start asking for.

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While newly approved pharmacotherapies such as glucagon-like peptide-1 receptor agonists (GLP-1 RAs) show efficacy, their clinical utility remains constrained by dose-dependent gastrointestinal complications, underscoring the urgent need for safer alternatives

Preclinical and observational data suggested possible benefits, spurring rigorous clinical testing