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Routine check-ins monitor your progress to ensure safety and effectiveness, allowing your provider to adjust your treatment as necessary

The answer appears to be both, though the relative contributions remain unclear

Although preliminary findings indicate that GLP-1Ra causes modest bone mineral density reduction and enhances bone remodeling, favoring resorption similar to the effects of calorie restriction, further research is needed on fracture-related outcomes in people living with obesity

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Most gastrointestinal adverse events were mild or moderate in nature, and no grade 4 or grade 5 gastrointestinal adverse events were observed