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Description
A pivotal moment occurred in October 2022, just four months after Mounjaros launch, when Elon Musk admitted on Twitter (X) that taking Wegovy was his secret for looking fit and healthy. The post, and a subsequent tweet in 2024 that he was taking Mounjaro, went viral and sparked widespread curiosity around GLP-1s and their effectiveness on weight loss
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Cryo-EM analysis of a complex involving an exendin-4 analogue, the GLP-1R and Gs protein revealed two receptor conformers with distinct modes of peptide-receptor engagement
