is glp 1 safe Why Everyone Excited About GLP-1 Medication? What Is GLP-1 and Why

Currently, the use of GLP-1 RAs in individuals with a personal or family history of medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia syndrome type 2 (MEN2) is contraindicated

38 Liraglutide Liraglutide is a 31 aa-long synthetic peptide drug attached to 16 carbon fatty acids (MW: 3751 g/mol) (Figure 1D)

Other Serious Conditions Linked to GLP-1 Medication While drug-induced gastroparesis is often life-altering, it is not the only serious complication associated with GLP-1 medications

60 MeissnerW.RemyP.GiordanaC.MaltteD.DerkinderenP.HoutoJ.et al (2024)

Appetite Suppression (Central Nervous System) GLP-1 RAs can cross the blood-brain barrier or act on circumventricular organs to target specific brain regions, including the hypothalamus, hindbrain, and mesolimbic reward system (Zheng et al., 2024)

Then we had Herman Pontzer on and we talked about metabolic adaptation from the burn side, right the reason you can't marathon your way to weight loss because your body's just going to adjust