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GLP-1 receptor agonists have become a cornerstone of personalized weight management, but surgery introduces new clinical considerations
Shaw C, Mortimer P, Judd PA
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On the basis of results of the most recent CVOTs (DAPA-HF, DAPA-CKD, EMPEROR-R), the FDA has approved dapagliflozin (2020) and empagliflozin (2021) to reduce risk for CV death and HF hospitalization in adults with HF and reduced ejection fraction regardless of whether they have diabetes [24, 25]
But, the idea is still controversial, and a large, nationwide trial of older adults, slated to test the hypothesis, hasn't started yet.
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