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These impressive results have led people to wonder: Do medications take the place of diet, exercise, and other lifestyle modifications

As they are thinly or un-myelinated, autonomic nerves may be especially susceptible to vascular and metabolic insult

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These are astounding results given both the magnitude of the weight loss and the time frame in which it occurred (gradual weight loss over 1.3 years) as rapid weight loss is known to be unhealthy and subject to the yo-yo effect