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This allows the medication to largely leave your system, reducing the risk of compounded side effects

A pooled analysis published in the National Institutes of Health PMC archive found tirzepatide reduced body weight more than semaglutide across different study designs, and a journal review summarized by the American College of Cardiology reported significantly greater weight loss with tirzepatide

Surgery 170(1):1317 Abdi Beshir S, Ahmed Elnour A, Soorya A, Parveen Mohamed A, Sir Loon Goh S, Hussain N et al (2023) A narrative review of approved and emerging anti-obesity medications

Obesity is a chronic, progressive disease and rates are on the rise worldwide

On days when pain or fatigue is worse, doing less or resting is fine

The medication also inhibits the release of glucagon from the pancreas, which is a hormone that causes the liver to release its stored carbohydrate and sugar into the bloodstream