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Wellness GLP-1s are making waves for a reason

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Bloom further reported that infusions of the PYY hormone lead to decreased eating by mice, rats and human volunteers (26) although its efficacy is controversial (27)

These statements have not been evaluated by the FDA

First, quantify patient preferences

N Engl J Med 375:311322 Ahrn B, Masmiquel L, Kumar H, Sargin M, Karsbl JD, Jacobsen SH, Chow F (2017) Efficacy and safety of once-weekly semaglutide versus once-daily sitagliptin as an add-on to metformin, thiazolidinediones, or both, in patients with type 2 diabetes (SUSTAIN 2): a 56-week, double-blind, phase 3a, randomised trial