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Umpierre, D., Ribeiro, P
[2] While topiramate can cause weight loss as a side effect, using it primarily for weight management is considered off-label in the UK and should only be considered under specialist care when indicated for its licensed uses

There is a significant unmet need for improved therapies that can produce robust and sustained metabolic benefits for patients

Pharmacological treatment is offered if the symptoms are not managed adequately with lifestyle changes
SUSTAIN-6 showed that semaglutide reduced major adverse cardiovascular events by 26%

New GLP-1 agonist guidance FAQs and patient information We've developed FAQs and patient information for clinicians to use when talking to patients using GLP-1/GIP receptor agonists