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Jendle J, Grunberger G, Blevins T, Giorgino F, Hietpas RT, Botros FT

GlaxoSmithKline cited commercial reasons (poor market uptake compared to Trulicity and Ozempic)

MR analysis indicated that genetically proxied GLP-1RAs were associated with a reduced risk of AF (odds ratio [OR] = 0.78, 95% confidence interval [CI] = 0.710.85, p = 4.45E-08, posterior probability of hypothesis 4 [PP.H4] = 0.007) and a lower risk of cardiac arrest and ventricular fibrillation (OR = 0.60, 95% CI = 0.420.85, p = 0.0039, PP.H4 = 0.018)

Increasing physical activity

doi: 10.3389/fimmu.2023.1148209, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] 107.Gharagozloo M, Galleguillos D, Jank L, Sotirchos ES, Smith MD, Garton T, et al

A newly released study that compared the weight loss and side effects experienced by 358 adults 65 and older who participated in trials of the drug semaglutide, or Wegovy, confirmed that seniors lost 15.5% of their body weight on average, while younger adults lost 15.6%, nearly exactly the same
