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The short-acting GLP-1 receptor agonists primarily lower postprandial blood glucose levels through inhibition of gastric emptying, whereas the long-acting compounds have a stronger effect on fasting glucose levels, which is mediated predominantly through their insulinotropic and glucagonostatic actions

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[DOI] [PMC free article] [PubMed] [Google Scholar] 10.Meier J.J

This delay in gastric emptying is also associated with increased satiety and reduced appetite, contributing to weight management