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Diabetes Care 33:730732 Migoya EM, Bergeron R, Miller JL et al (2010) Dipeptidyl peptidase-4 inhibitors administered in combination with metformin result in an additive increase in the plasma concentration of active GLP-1

Furthermore, some individuals taking these medications might experience changes in their eating habits due to decreased appetite, sometimes leading to nutritional deficiencies if a balanced diet is not maintained

Meeting Protein, Calorie and Fiber Needs: GLP-1s may lower your appetite so much that it becomes difficult to eat enough

Here, we cover some of the conditions with active clinical trials that may not be getting as much attention as the weight loss and diabetes cases

GLP-1 therapy can be reconsidered once psychiatric symptoms are managed

In China, the patent expires slightly earlier, in 2026