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A pivotal moment occurred in October 2022, just four months after Mounjaros launch, when Elon Musk admitted on Twitter (X) that taking Wegovy was his secret for looking fit and healthy. The post, and a subsequent tweet in 2024 that he was taking Mounjaro, went viral and sparked widespread curiosity around GLP-1s and their effectiveness on weight loss

Use of blockbuster anti-obesity drugs like Wegovy and Zepbound is growing, with about 1 in 8 adults in the U.S

evaluate the translational evidence supporting GLP-1RAs as candidate disease-modifying therapies for neurodegenerative diseases in this installment to the JCIs Review

Donovan includes a thought-provoking assessment of the effects of the GLP-1s in equality and society, calling out that, In most societies there is prejudice against people who are overweight or obese, more pronounced the case for women The more anti-obesity drugs are used recreationally rather than as a prescription written for obesity, the more likely patients will have to pay for the drugs out-of-pocket restricting recreational access to people with higher incomes Social media has raised the importance of physical appearance and for some people increased the perceived importance of appearances

Functional trainers are also joint-friendly by design

These insights may open new avenues to bypass the surgery and obtain the same results with targeted drugs.