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This article thoroughly traces the developmental milestones of GLP-1 drugs, from their initial discovery to their clinical application, detailing the evolution of diverse GLP-1 medications along with their distinct pharmacological properties

This includes the protein known as Amuc_1100, which we here rename as pilus-associated signaling (PAS) protein , the P9 protein encoded by Amuc_1631, the short-chain fatty acids acetate and propionate, and cell envelope components, such as phosphatidylethanolamine and peptidoglycan.

The paper concludes by discussing the potential of LLMs and social media data in enhancing pharmacovigilance and providing patient-centered insights

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Prednisone increases blood glucose while semaglutide lowers it, potentially altering medication efficacy or tolerability