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Referral and Management Considerations Dermatology referral should be considered when the diagnosis remains uncertain or when systemic involvement is suspected
Finally, GLP-1RAs decrease ROS to ease oxidative stress and shield mitochondria (94)

These include nausea, vomiting, diarrhoea, constipation, abdominal discomfort, and reduced appetite, as documented in the UK SmPC

10.1016/j.brainres.2011.12.063 26 CraftS.WatsonG

Stefano GB (2026) Convergent Mitochondrial and Reward-Circuit Mechanisms Underlying Appetite, Addiction, and GLP-1 Therapeutics

Egecioglu, Steensland, et al., 2013