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This affordability equation is expected to shift significantly after the patent on Semaglutide expires in China and India in 2026

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GLP-1 receptor agonists such as semaglutide are primarily designed for blood sugar control and weight management, but emerging research suggests indirect effects on stress hormone pathways

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Combining naltrexone and semaglutide may enhance weight loss through different biological pathways, but safety and efficacy depend on individual health factors and medical supervision

Phase 3 programmes also evaluated long-term safety, tolerability, and metabolic outcomes, forming the basis for subsequent regulatory approvals in certain jurisdictions