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The GLP-1 revolution is still in the early stages

S., Pduraru, L., Yahya, G., et al
This is important because it indicates that any increase in systemic GLP-1 levels (for example through medication) could potentially influence the amount that reaches the joint. Tue Wenzel Kragstrup, MD, PhD The next step (in this research) is to find out whether GLP-1-based drugs reach the joints in high enough concentrations to have biological effects there, Kragstrup continued

Sustainable weight loss at 12 pounds weekly is safer and less likely to cause energy crashes than aggressive restriction

And as more information has come about, Ive changed my mind about how I think about these medications

Formation of N-nitrosamine drug substance related impurities in medicines: a regulatory perspective on risk factors and mitigation strategies