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The subcutaneous route ensures gradual, sustained absorption into the bloodstream, which is essential for maintaining therapeutic drug levels and minimising side effects

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Rapid enzymatic degradation limited oral bioavailability, short plasma half-lives, and pleiotropic signaling profiles confined peptides largely to hormone replacement therapies or niche endocrine indications

In a meta-analysis of 43 randomized trials with 22,528 patients triglyceride levels were decreased by 2 mg/dL (145)

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I do not think people should be left alone navigating this complex landscape of these medications without a lot of contact with their clinician and provider