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Watch for signs of excessive dosing including water retention, joint discomfort, carpal tunnel symptoms, or blood sugar elevation

They follow predictable patterns that correlate with dose tier, escalation speed, and individual tolerance

Given tirzepatide shorter half-life of about 5 days, the washout window can be shorter than when switching in the other direction

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Sharps containers can be reused and are often available for less than $10 at your local pharmacy

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