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Semaglutide is available under several brand names: Ozempic: FDA-approved for type 2 diabetes (doses up to 2 mg weekly) Wegovy: FDA-approved for chronic weight management (doses up to 2.4 mg weekly) Rybelsus: Oral tablet form approved for type 2 diabetes Semaglutide has the most extensive clinical evidence of any GLP-1 medication for weight loss, with the STEP trial program providing robust data across multiple patient populations

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doi:10.1007/s00018-007-7080-4 114
