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An effective approach combines the right fiber type with proper hydration and timing

Most patients regain a substantial portion of weight within 1 year of discontinuation if no maintenance strategy is in place

Thrive GLP-1 might produce 5-8 pounds if everything works perfectly

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As of March 2026, two trials are actively recruiting new participants: the Maintenance trial (NCT06859268, testing dose reduction after initial weight loss) and a new enrollment trial (NCT07232719, 250 participants with obesity or overweight)