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Description
In the STEP 1 trial , adults without diabetes who took 2.4 mg of semaglutide once a week lost 14.9% of their body weight on average over a 68-week period

Potential Benefits
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18 One design-around strategy involves switching to buffer-free systems

Clinical trial data shows that nausea peaks in the first 12 weeks of tirzepatide therapy, then gradually declines over the following 46 weeks

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