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While it can vary by person, some people may start noticing a decrease in appetite within the first few weeks of starting semaglutide, and for many more people, a more noticeable reduction in appetite occurs around 8 to 12 weeks after starting the medication as the dosage is increased

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[DOI] [PMC free article] [PubMed] [Google Scholar] Galera C, Clemente F, Alcantara A, Trapote MA, Perea A, Lopez-Delgado MI, Villanueva-Penacarrillo ML, Valverde I