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However, further large-scale RCTs are warranted to validate these results and elucidate the underlying biological mechanisms
These changes in components of appetite are suspected to be major contributors to the measured decrease in ad libitum food intake with tirzepatide compared with placebo

MAIN COMPOUND PATENTS The active ingredient, semaglutide, as used in Novo Nordisks products Ozempic, Rybelsus and Wegovy is protected by two key compound patents, U.S
[82] In December 2017, the injectable version with the brand name Ozempic was approved in the US for use by people with diabetes, [30] [83] and, in January 2018, in Canada

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