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For drugs in BCS Class I (high solubility, high permeability), such as warfarin and oral contraceptives[43], co-administration with GLP-1RAs resulted in delayed time to maximum concentration (t max ) and reduced maximum concentration (C max )

Additionally, clinicians commonly administer opioids for pain management, which can also worsen this effect by further reducing bowel motility

2024;12:e17891
