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Low-density lipoproteins are pro-atherogenic and have been linked to intracranial and extracranial atherosclerotic disease

It is important to distinguish between dark urine caused by concentration (which appears deep yellow to amber and clears with increased fluid intake) and abnormal pigmentation suggesting pathology (such as tea-coloured urine indicating bilirubin, or red-brown urine suggesting blood or myoglobin)

The percentage of GLP- 1R positive cases for Ins pos , Ins neg , and insulinoma was 31%, 0%, and 84%, respectively

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Bharucha AE, Locke GR, Murray JA

This is why GLP-1 is used as an active ingredient in GLP-1 program to help control appetite, ultimately leading to weight loss