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All GLP-1 RAs other than Saxenda and Wegovy have the indication of T2DM and are subsidized only for patients with T2DM who first tried metformin, sulphonylureas or insulin, or where these are not appropriate

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This is a well-documented risk

Clinical trial data submitted to regulatory authorities, including the MHRA and European Medicines Agency (EMA), document headache as an adverse event across different GLP-1 medications, with varying frequencies depending on the specific drug and dosage

Metabolic responses to acute and chronic L-dopa administration in patients with parkinsonism

In a statement, the company's CFO Ruby Kam said, "Costs for medical care and medications for our members have escalated rapidly and spending is now growing at the fastest rate in more than a decade