glp 1 and alcohol use disorder IUPHAR review – Glucagon-like peptide-1 (GLP-1) substance disorders: An emerging pharmacotherapeutic target Medscape | Once weekly semaglutide
Description
Glucagon-like peptide-1 receptor agonist liraglutide inhibits endothelin-1 in endothelial cell by repressing nuclear factor-kappa B activation
doi: 10.1016/j.diabres.2003.08.015 267 GaoYZhangYZhuJLiBLiZZhuWet al
Its side effects are similar to semaglutide
Key Takeaways Semaglutide is injected subcutaneously, with the abdomen, thigh, and back of the upper arm being the recommended injection sites
GLP-1 is a naturally occurring hormone found in the small intestine that works to release insulin from the pancreas
Of those, 4 RCTs [1, 2, 4] as SURMONT-OSA Trial by Malhotra et al
