exenatide vs semaglutide History of glucagon-like peptide-1 receptor agonists No Difference Seen in Risk

Change in Body Weight (%) from Baseline to Week 68 (Study 2) with WEGOVY Injection Observed data from in-trial period including imputed data for missing observations (RD-MI)

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weight regain occurs after discontinuation STEP 5 (extended duration, N = 304): 104-week treatment duration (2 years) Mean weight loss: 15.2% at week 104 Weight loss plateaus between weeks 60 and 68, then remains stable with continued treatment The consistency across trials is notable

These include: Nausea Vomiting Diarrhea Stomach pain Constipation People in Chandler, AZ undergoing semaglutide treatment report that most side effects tend to decrease over time as the body adjusts to the medication