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Second, retatrutide does not cause impairment

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Limitations of Weight Loss Medications: Modest weight loss: Compared to bariatric surgery, weight loss with medications tends to be more modest, typically in the range of 5-15% of body weight

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In a January 2024 update, the FDA stated that its preliminary evaluation has not found evidence that GLP-1 RAs cause suicidal thoughts or actions, based on available clinical trial data and adverse event reports (FDA Drug Safety Communication, 2024)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 131.Chen S, et al

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Common side effects may include mild nausea or stomach discomfort, temporary fatigue or dizziness, and occasional constipation or diarrhea

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In the United States, the FDA suggests that adults limit their caffeine intake to no more than 400 mg per day

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