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Decrease in serum insulin level shows improved insulin sensitivity under metabolic stress (Figure 1B)

If you are taking a GLP-1 medication and are considering discontinuing it, you should first speak with your healthcare professional

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It therefore seems that GLP-1/exendin-4 might be acting in the VMH and LH, interacting with the AMPK/S6K signalling pathways, and modulating the activation status of AMPK and S6K in response to nutrient fluctuations