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VX-765 is currently undergoing clinical investigation in epilepsy (clinical trial identifier: NCT01048255) and psoriasis (clinical trial identifier: NCT00205465) without any reports of toxicity yet

Semaglutide has demonstrated safety in clinical trials extending beyond two years, with most side effects being mild and self-resolving

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Heres a sample dosing chart: Weeks 1-4: 2.5 mg once weekly Weeks 5-8: 5.0 mg once weekly Weeks 9-12: 7.5 mg once weekly Weeks 13-16+: 10 mg once weekly Step-Up Therapy: 12.5 mg or 15 mg once weekly If needed, your doctor will set up a plan that starts with a low dose and slowly increases over time

Higher doses (8-12 mg) are designed to maximize weight loss through stronger appetite suppression, which can actually work against muscle building goals by making adequate nutrition challenging

The rapid adoption and commercial formulary access for Wegovy, along with efforts to increase supply, have contributed to its market dominance