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Key variants like GLP1R rs6923761 and GIPR rs1800437 affect how strongly your GLP-1 receptors respond to medication, which becomes especially important when your digestive anatomy has been altered by surgery

Remember that weight can fluctuate due to factors like water retention, so dont be discouraged by minor changes

For individuals managing weight or metabolic health while breastfeeding, this decision requires balancing treatment goals with infant safety

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Semaglutide, a long-acting GLP-1 analogue, for the management of early-onset obesity due to MC4R defect: A case report