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80 Phlorizin, the first SGLT-2i, is a naturally occurring chalcone compound discovered in apple bark in the 1850s by French researchers

[DOI] [PMC free article] [PubMed] [Google Scholar] 13.Heppner K.M., Kirigiti M., Secher A., Paulsen S.J., Buckingham R., Pyke C., et al

A principal component analysis of the KEGG pathway showed greater similarities between the AmII and AmIII genomes, whereas AmI genomes differed significantly
