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Novo Nordisk's SELECT cardiovascular outcomes trial demonstrated that semaglutide 2.4 mg could reduce the risk of major adverse cardiovascular events by 20% in adults who are overweight or have obesity

Tirzepatide, made by Eli Lilly, is used to treat Type 2 diabetes, under the brand name Mounjaro, and to treat obesity, under the brand name Zepbound

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The included metabolic testing is a genuine value-add that many competitors charge extra for or skip entirely

The slightly higher number of AEs in the dosing conditions trial compared with the food-effect trial, particularly gastrointestinal AEs, may be explained by the difference in dosing regimen between the two trials

If you experience nausea while taking semaglutide, it may be helpful to reduce your intake of caffeinated beverages, as caffeine can sometimes exacerbate nausea