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However, retatrutide targets three hormone pathways involved in weight management, while tirzepatide targets two
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Serious hypersensitivity reactions (e.g., anaphylaxis, angioedema) have been reported with GLP-1 receptor agonists

If you suspect you're experiencing side effects from either medicine, you can report them through the MHRA Yellow Card scheme, which helps monitor the safety of medicines in the UK

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