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As patients lose weight on semaglutide, their cardiovascular system often benefits through reduced strain on the heart and improved blood vessel function

Gudbergsen H, Overgaard A, Henriksen M, Whrens EE, Bliddal H, Christensen R et al (2021) Liraglutide after diet-induced weight loss for pain and weight control in knee osteoarthritis: a randomized controlled trial
That exclusion has stood in stark contrast to mounting evidence that obesity is a chronic, relapsing disease that drives cardiovascular disease, kidney failure, sleep apnea, and more

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Wegovy and Saxenda are two drugs for weight loss with necessary diet modification and exercising, but have differences