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I once had a colleague who was thin but ate so much, and all I wanted was to have some of what she had, she says

Today's oral GLP-1s give 13-15% weight loss at 36 weeks (orforglipron Phase 2)

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Although hydration remains crucial, other fears about GLP-1 use in older adults may turn out to be more theoretical than real

The gradual onset helps your body adjust and gives it time to establish sustainable eating patterns that support long-term maintenance

Ann Intern Med 150(9):604612
