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The development of dual GIPRGLP1R coagonists that bind to either one or the other receptor (sequence-mixed dual agonists) has emerged as an innovative therapeutic strategy for obesity and type 2 diabetes

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New research indicates that maintaining meaningful weight loss after starting GLP-1-based therapies could play an important role in reducing the risk of multiple obesity-related diseases.

When appetite decreases, nutrition has to work harder

GLP-1 RAs mimic naturally occurring GLP-1, an enterohormone produced in response to oral intake that regulates glucose metabolism and promotes weight loss

Were now seeing a real shift: from weekly injections to once-daily pills Two oral GLP-1 options are now leading this transition: #Wegovy pill (oral semaglutide) first to market #Foundayo (orforglipron) newest entrant But heres what you must know