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[DOI] [PubMed] [Google Scholar] 77.Watson A., Nong Z., Yin H., ONeil C., Fox S., Balint B., Guo L., Leo O., Chu M.W.A., Gros R., et al

Serious but rare risks include hypoglycemia (low blood sugar), acute pancreatitis (severe, persistent abdominal pain often with vomiting), acute gallbladder disease (sudden right-upper abdominal pain that may radiate to the shoulder), and severe allergic reactions with breathing difficulty or swelling of the lips, tongue, or throat

EudraVigilance pharmacovigilance data When we look beyond controlled trials to real-world reporting, the picture gains complexity

Nausea management strategies include: Eating smaller, more frequent meals rather than three large meals Avoiding high-fat, greasy, or heavily spiced foods that delay gastric emptying further Staying upright for 2-3 hours after eating to facilitate gastric emptying Ensuring adequate hydration throughout the day Considering anti-nausea medications if symptoms are severe (note: if metoclopramide is used, it should be short-term only under medical supervision due to risk of tardive dyskinesia) [18] [19] Constipation affects approximately 20-30% of patients and results from slowed gastrointestinal transit throughout the digestive tract