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[DOI] [PubMed] [Google Scholar] 77.Watson A., Nong Z., Yin H., ONeil C., Fox S., Balint B., Guo L., Leo O., Chu M.W.A., Gros R., et al

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Serious but rare risks include hypoglycemia (low blood sugar), acute pancreatitis (severe, persistent abdominal pain often with vomiting), acute gallbladder disease (sudden right-upper abdominal pain that may radiate to the shoulder), and severe allergic reactions with breathing difficulty or swelling of the lips, tongue, or throat

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EudraVigilance pharmacovigilance data When we look beyond controlled trials to real-world reporting, the picture gains complexity

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Nausea management strategies include: Eating smaller, more frequent meals rather than three large meals Avoiding high-fat, greasy, or heavily spiced foods that delay gastric emptying further Staying upright for 2-3 hours after eating to facilitate gastric emptying Ensuring adequate hydration throughout the day Considering anti-nausea medications if symptoms are severe (note: if metoclopramide is used, it should be short-term only under medical supervision due to risk of tardive dyskinesia) [18] [19] Constipation affects approximately 20-30% of patients and results from slowed gastrointestinal transit throughout the digestive tract

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