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Thinking about starting treatment, or not sure which route fits your life
Some providers prescribe metformin as a bridge during GLP-1 discontinuation, particularly for people with insulin resistance or prediabetes
Organ protection: Lower 10-year risk of MACE, nephropathy, and retinopathy than GLP-1 therapy alone

Rapid weight loss and reduced caloric intake can lead to deficiencies in vitamins and minerals

GLP-1RA therapy inhibits glucagon secretion, at least transiently delays gastric emptying, and reduces appetite and food intake [60,61]

They, and then GLP ones, remember I said they lower systemic inflammatory burden
